Editing Disease

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<includeonly>:''Main article: [[Disease]]''</includeonly>{{About|treatable illnesses|physical damage|Injury|chronic health conditions|Ailments}}

'''Diseases''' are temporary and treatable ailments, that pass away after a certain amount of time or treatment.

== Contract ==
Most diseases are contracted as part of an [[event]]. Your colony's [[biome]] determines how common diseases are, as well as how common each disease is. However, some diseases happen situationally, regardless of biome:
*[[Infection]] may occur after a bleeding [[injury]], burn, or frostbite is inflicted. Tending the injury in a clean room reduces the chance of infection.
*[[Lung rot]] occurs randomly when inhaling enough [[rot stink]].
*[[Blood rot]]{{RoyaltyIcon}} and [[paralytic abasia]]{{RoyaltyIcon}} are exclusively part of [[quest]]s, while [[infant illness]]{{BiotechIcon}} can only happen during [[Reproduction#Birth|birth]].

Note that diseases are '''not contagious''' in RimWorld. Disease does not ever spread between colonists, though disease events often simulate "outbreaks: by inflicting multiple colonists at the same time.

The drug [[penoxycyline]] protects against [[Malaria]], [[Plague]], and [[Sleeping sickness]]. The disease event still happens, but colonists will not be affected.

== Summary ==
Humans and animals can get diseases. Most diseases uses the ''severity'' mechanic. As a disease progresses, its symptoms progressively get worse. If a fatal disease's severity reaches 1.0 (100%), then [[death]] occurs. Most diseases go from minor -> major -> extreme. How fast a disease progresses depends on the disease itself.

== Diseases ==
'''Note:''' Base values of severity and immunity gain speed used in the table.<br>Treatment's reduction of severity depends on tend quality. 50% tend quality equals half the reduction.
<div><li style="display: inline-table;">
{| {{STDT| c_10 text-left}}
|-
! Disease!! Fatal? !! Description !! Severity !! Treatment 
|-
| [[Infection]] || {{Check}} || Generic infection of individual [[injury|wounds]]. 
*Fast moving and dangerous. 
** < 1.25 days to kill if untreated. <1.5 days for immunity.
*Mild symptoms until extreme severity (>0.87). ({{++|5%}} to {{++|12%}} pain) 
|
* Severity: +0.84 / day
* Immunity: +0.644 / day
* Treatment: -0.53 severity / day <br>(at 100% quality)
| 
* Bed rest and medicine
* Amputation of infected body part
|-
| [[Flu]] || {{Check}} ||  ''Relatively'' mild and common disease.
*Non-elderly adults can survive without treatment, with just bedrest.
*Lowers [[consciousness]], [[manipulation]], [[breathing]] ({{--|5%}} to {{--|20%}}).
|
* Severity: +0.249 / day
* Immunity: +0.239 / day
* Treatment: -0.077 severity / day <br>(at 100% quality)
| 
* Bed rest and medicine
|-
| [[Malaria]] || {{Check}} || Common in tropical [[biomes]].
* Attacks [[blood filtration]], slowing immunity speed.
* Later stages cause [[pain]] and reduces [[consciousness]].
| 
* Severity: +0.370 / day
* Immunity: +0.314 / day
* Treatment: -0.232 severity / day<br>(at 100% quality)
| 
* Bed rest and medicine
|-
| [[Plague]] || {{Check}} || Fast moving and ''extremely'' painful.
* ~1.5 days to kill if untreated.
*Constant [[pain]] ({{++|20%}} to {{++|85%}}).
*Also reduces [[consciousness]] and [[manipulation]] (up to {{--|30%}}).
||
* Severity: +0.666 / day
* Immunity: +0.522 / day
* Treatment: -0.362 severity / day <br>(at 100% quality)
|
* Bed rest and medicine
|-
| [[Sleeping sickness]] || {{Check}} || Very slow-moving infection. Native only to [[biome|rainforests and swamps]].
*Relatively easy to treat if rested. 
* Threat is the amount of rest / medicine required.
*Mainly lowers [[consciousness]] & [[manipulation]] ({{--|2%}} to {{--|20%}}).
||
* Severity: +0.12 / day
* Immunity: +0.11 / day
* Treatment: -0.07 severity / day <br>(at 100% quality)
| 
*  Bed rest and medicine
|-
| [[Scaria]] || {{Check}} || Drives [[animal]]s to become [[manhunter]]s. 
*Exclusive to animals in [[manhunter pack]]s. 
*Humans and colony animals immune.
||
* Kills in 5 days, unless cured
| 
* Surgery
**{{icon small|medicine}} 3 [[medicine]]
**[[Skills#Medical |Medical Skill]] 8+
|-
| [[Lung rot]] || {{Check}} || 
Occurs after enough exposure to [[rot stink]]. Avoid rot stink to avoid.
* Resisted by sources of [[Toxic Environment Resistance]].
* Easily treatable overall. Can drain medicine.
* Impairs [[breathing]] slightly. Minimal symptoms overall.
||
* Severity: +0.300 / day
* Treatment: -1.000 severity / day <br>(at 100% quality)
|
* Medicine
Resolves from:
*Min {{ticks/gametime|360000}}
*Max {{ticks/gametime|480000}}
|-
| [[Gut worms]] || {{cross}} || Doubles hunger rate.
*Also painful ({{++|20%}} pain).
|| 
* No progression
* Cured at 300% total Tend Quality
|
* Medicine (48hr per tend)
* Stomach replacement or removal
|-
| [[Muscle parasites]] || {{cross}} || Heavily impairs work.
*Significant tiredness.
*Lowered [[manipulation]] and [[movement speed]] ({{--|30%}}).
*Also painful ({{++|20%}} pain).
||
* No progression
* Cured at 300% total Tend Quality
| 
* Medicine (48hr per tend)
|-
| [[Fibrous mechanites]] || {{cross}} || Very long-lasting, but ''improves'' working.
*Painful, significant tiredness.
*Significantly increases [[manipulation]], [[movement speed|moving]] and [[blood pumping]] ({{+|50%}} to all).
||
* Severity: +0.25 / day
* Treatment: -1.00 severity / day <br>(at 100% quality)
| 
* Medicine
**Prevents pain increase only
Resolves from:
*Min {{ticks/gametime|900000}}
*Max {{ticks/gametime/days|1800000}}
|-
| [[Sensory mechanites]] || {{cross}} || Very long-lasting, but ''improves'' many stats.
*Painful, significant tiredness.
*Significantly increases [[sight]], [[hearing]], and [[talking]] ({{+|50%}} to all).
*Increases [[manipulation]] ({{+|30%}}).
||
* Severity: +0.25 / day
* Treatment: -1.00 severity / day <br>(at 100% quality)
| 
* Medicine
**Prevents pain increase only
Resolves from:
*Min {{ticks/gametime|900000}}
*Max {{ticks/gametime/days|1800000}}
|-
| [[Blood rot]]{{RoyaltyIcon}} || {{Check}} || ''Extremely'' long lasting blood affliction.
*[[Quest]] only.
*Mild and easily treated, but can be a drain on medicine.
||
* Severity: +0.40 / day
* Treatment: -1.00 severity / day <br>(at 100% quality)
|
* Medicine
* Surgery for immediate cure
**{{icon small|Glitterworld medicine}} 10 [[glitterworld medicine]]
**[[Skills#Medical |Medical Skill]] 5+
Resolves from:
* Min {{ticks/gametime/days|60000*30}}
* Max {{ticks/gametime/days|60000*40}}
|-
| [[Paralytic abasia]]{{RoyaltyIcon}} || {{Cross}} || Complete immobility. ''Extremely'' long lasting.
*[[Quest]] or [[Events#Transport pod crash|transport pod crash]] only.
||
* No progression
* 1% per day to instantly cure
|
* Waiting
* Surgery for immediate cure
**{{icon small|Glitterworld medicine}} 10 [[glitterworld medicine]]
**[[Skills#Medical |Medical Skill]] 5+
Always resolves after:
* Min {{ticks/gametime/days|60000*30}}
* Max {{ticks/gametime/days|60000*40}}
|-
| [[Infant illness]]{{BiotechIcon}} || {{Check}} || Inflicted after a sick [[Reproduction#Birth|birth]] of a [[baby]].
*4 different types of illness, from mild to grave. Switches every 1-3 days.
*Uniquely, reducing severity to 0 cures the disease (no immunity required).
||
* Starts as Major severity (0.40)
* Severity gain depends on the type
** From -0.25 to +0.5 severity / day
* Immunity: +0.10 / day
* Treatment: -0.35 severity / day <br>(at 100% quality)
| 
* Medicine and bed rest
|-
|}
</li><div>

== Treatment ==
Most diseases can be tended to, just like an [[injury]] or [[ailment]], by a [[Doctoring|Doctor]] pawn and when the afflicted pawn is assigned to [[Work|Patient]] themselves. Tend Quality is determined by a variety of factors, including the doctor's [[skill]] and the quality of [[Medicine]] used. Generally, higher quality tends reduce the total time until recovery, though mechanics vary. How often a disease can be tended depends on the disease itself.

There are 3 types of diseases to tend to:
* The disease will progress over time, and treatment slows down progression. Immunity is gained over time, dependent on [[Immunity Gain Speed]] and independent of tend quality. Once immune, the disease will slowly fade and the colonist will stop being a patient. This applies to most fatal diseases, including the [[flu]], [[infection]], and [[plague]].
* The disease does not progress. Treatment must reach a ''total tend quality'' (300%) before the disease is cured. For example, 4 tends at 80% quality would equal 320% total tend quality. Applies to [[gut worms]] and [[muscle parasites]].
* The disease progresses over time, and treatment slows and even prevents progression. The disease fades only after a certain time. Applies to [[lung rot]], [[fibrous mechanites]], [[sensory mechanites]], and [[blood rot]].{{RoyaltyIcon}}

Certain diseases have specialized cures. For example, [[infection]] in a non-vital part can be cured by amputating or [[Artificial body part|replacing]] a limb, [[blood rot]] can be instantly cured with [[glitterworld medicine]], and [[gut worms]] can be treated by replacing the stomach. In addition, a [[healer mech serum]] immediately cures any disease.

=== Immunity gain ===
{{Main|Immunity Gain Speed}}
Some diseases are a race between the increasing severity of the disease and the increasing immunity to it. This immunity gain is controlled by several factors:
* Base immunity gain speed for the particular disease. 
* InfectionLuck, an uncontrollable generated value that adds randomness to the diseases progression. Each disease has a variance in Immunity gain speed of 20% up or down. 
* The [[Immunity Gain Speed]] stat of the patient

Immunity Gain Speed is affected by the following:
* '''[[Food]]''': Pawns above 12.5% [[Saturation]] do not have any penalties to immunity.
* '''[[Rest]]''': Actively resting gives a bonus to speed. Resting in any [[bedroll]] or [[bed]] increases the stat, a [[hospital bed]] increases it further, and a hospital bed with an attached [[vitals monitor]] increases it the most.
* '''Age''': As a pawn gets closer to and past their species' life expectancy, immunity gain speed decreases. 
** For baseline humans, immunity gain speed is gradually lost after age 54. [[Genes]]{{BiotechIcon}} like [[Genes#Mild cell instability|cell instability]] can affect the pawns lifespan and, in turn, affect this progression.{{Check Tag|Verify|Verify and also confirm on Immunity Gain Speed page}}
* '''[[Blood Filtration]]''': Mostly increased via [[luciferium]]. Reduced with [[kidney]] or [[liver]] damage, slightly improved with a [[detoxifier kidney]]{{BiotechIcon}}.
* '''Direct boosts''': The [[Super-immune]] trait, [[Immunoenhancer]]{{RoyaltyIcon}}, and [[gene]]s{{BiotechIcon}} can increase immunity speed.

Note that these only apply to diseases with immunity mechanics. For example, you don't need to give a pawn with [[gut worms]] bedrest.

== Disease frequency ==

=== Disease frequency by AI storyteller ===
Disease frequency is controlled directly by the [[AI_Storytellers#Disease frequency|Disease frequency]] AI storyteller setting. 

This value can be changed in custom storyteller settings, but has the following default values by difficulty:

{| {{STDT| c_08 text-center}}
! Difficulty !! Disease interval multiplier
|-
| Peaceful || 3
|-
| Community builder || 2.5
|-
| Adventure story || 1.3
|-
| Strive to survive || 1.0
|-
| Blood and dust || 0.95
|-
| Losing is fun || 0.9
|-
|}

=== Disease frequency by [[biomes]] ===
{{stub|section=1|reason = Use [[Biomes]] as references but playtest against the last version or just inspect source code and resource files.}}

== Version history ==
* [[Version/0.7.581|0.7.581]] - Added with flu, plague, malaria, sleeping sickness.
* [[Version/0.9.722|0.9.722]] - Diseases can now cause vomiting.

[[Category:Health]]
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