Editing Penoxycyline

<includeonly>''Main Article: [[Penoxycyline]]''</includeonly>
<noinclude>{{Define|Drug
| always haulable = true
| def name = Penoxycyline
| description = A drug for blocking various infections. Blocks malaria, sleeping sickness, and plague. Take every five days.
| deterioration rate base = 2.0 
| draw gui overlay = true
| flammability base = 1.0
| food preference = NeverForFood
| graphic class = Graphic_StackCount
| graphic path =  Things/Item/Drug/Penoxycyline
| label = penoxycyline
| beauty base = -6
| market value base = 32
| max hit points base = 50
| mass base = 0
| max num to ingest at once = 1
| nutrition base = 0
| parent name = MakeableDrugPillBase
| path cost = 15
| preferability =
| resource readout priority = Last
| rotatable = false
| selectable = true
| social properness matters = true
| sound eat = 
| stack limit = 400
| taste = 
| tech level = industrial
| thing class = Drugs
| ticker type = 
| use hit points = true
| work to make base = 9
<!--
- Drug Parameters -->
| addictiveness = 0
| blood filtration factor =
| blood filtration offset =
| blood pumping factor =  
| blood pumping offset =
| breathing factor =  
| breathing offset =
| consciousness factor = 
| consciousness offset =
| drug category = medical
| global work speed offset = 
| hearing factor =  
| hearing offset =
| hunger factor =
| hunger offset =
| is pleasure drug = false
| joy kind =
| joy offset = 
| manipulation factor =  
| manipulation offset =
| metabolism factor =  
| metabolism offset = 
| moving factor =  
| moving offset =
| pain factor =
| pain offset = 
| prevents infection = malaria, sleeping sickness, plague
| rest fall factor =
| rest offset = 
| sight factor =  
| sight offset =
| talking factor =
| talking offset = 

}}</noinclude>
<noinclude>
{{Info|A drug for blocking various infections. Blocks malaria, sleeping sickness, and plague. Take every five days.
}}</noinclude>

<includeonly>
{|class = "wikitable c03" 
|-
!colspan="2" scope="col" style="text-align: left" | Drug info
|-
|Addictiveness ||  {{#show: Penoxycyline | ?addictiveness | link=none }}%
|-
|Market value || ${{#show: Penoxycyline | ?Market Value Base | link=none }}.00
|-
|Hit points || {{#show: Penoxycyline | ?Max Hit Points Base | link=none }}
|-
|Work to make || {{#show: Penoxycyline | ?Work To Make Base | link=none }}
|}
</includeonly>

<noinclude>
==Gameplay Overview==
Penoxycyline is a medical drug in RimWorld which was introduced in Alpha 16, and succeeds Malari-Block. Unlike its predecessor, Penoxycyline blocks against 3 diseases: [[malaria]], [[sleeping Sickness|sleeping sickness]], and the dreaded [[plague]] - whereas Malari-block only blocked against malaria.

Like Malari-Block; Penoxycyline can either be purchased from traders, or crafted at a [[drug lab]] - but for a mere 3 [[neutroamine]] as opposed to the 5 which Malari-block took. However, in order to make Penoxycyline, you need to have [[research#PenoxycylineProduction|penoxycyline production]] researched, which in turn requires [[research#DrugProduction|drug production]], and Neutroamine has to either be purchased from traders, or found in cargo pods.

Penoxycyline can be administered if one has one of the diseases it protects against, and doing so will boost the immunity to 61% if it's lower than that.

Penoxycycline offers true immunity to plague & sleeping sickness for 12 hours, and malaria for 8 hours. After that period, it reduces the probably of that particular pawn getting sick (diseases cannot be acquired at 60%+ immunity, and Penoxy sets it to 61%, so there is a brief time before it decays below the threshold)

The weird part is that the game first picks how many pawns will get sick, regardless of immunity, and then next picks which pawns get sick, weighted by immunity. If only one of your pawns has taken penoxy, and took it 24 hours ago, that pawn is 1/50th as likely to get sick as the other pawns. But if all of your pawns have taken it 24 hours ago, they're all just as likely to get sick and the same number of pawns total will get sick. But they'll still be starting at 59% immunity, pretty much guaranteeing survival, and a very short period of actual sickness. (A young, healthy pawn will be at 90%+ immunity when the plague/sleeping sickness is revealed; malaria never revealed at all).

For plague & sleeping sickness, I would not recommend Penoxycycline prophylaxis for all healthy pawns; it can be taken reactively and still add 30%+ immunity, eliminating the need for bed rest or treatment to survive (and if treatment is provided it won't reach serious stages).

Malaria does need proactive Penoxycycline. A healthy pawn will develop 55% immunity in the 4.6 days it takes to reveal itself, so reactive penoxy only adds 5%. Penoxy taken every 5 days will maintain a minimum of 46% immunity to malaria, so healthy pawns will never have a visible Malaria infection. But taken every 9 days, a healthy pawn will still develop immunity before malaria hits Major severity without any treatment or bed rest. A solo jungle explorer looking to conserve their supply might stretch it out to every 12 days (which will avoid extreme without any treatment or bed rest), or if they're particularly brave/desperate, every 15 days (but then there is a small risk that bed rest will be necessary). Taken every 20 days, Penoxy offers no guaranteed immunity, but on average will cut off 2.5 days before immunity is acquired.
</noinclude>

<noinclude>
{{nav/drugs}}
</noinclude>
@@ Line 1: / Line 1: @@
-{{Infobox main|drug
+<includeonly>''Main Article: [[Penoxycyline]]''</includeonly>
-| name = Penoxycyline
+<noinclude>{{Define|Drug
-| image = Penoxycyline b.png
-| description = A drug for preventing infections before they take hold. Blocks malaria, sleeping sickness, plague.{{Sic}} Must be taken every five days to remain effective.<br/>This drug only prevents new infections. It does not cure existing infections - even those that are not yet discovered.
-<!-- Base Stats -->
-| type = Drug
-| type2 = Medical Drug
-| tech level = Industrial
-| marketvalue = 18
-| stack limit = 150
-| mass base = 0.005
-| beauty = -4
-| hp = 50
-| deterioration = 2
-| flammability = 0.7
-| rotatable = false
-| path cost = 14
-<!-- Ingestion -->
-| addictiveness = 0
-| max num to ingest at once = 1
-<!-- Creation -->
-| production facility 1 = Drug lab
-| research = Penoxycyline production
-| work to make = 600
-| work speed stat = Drug Synthesis Speed
-| resource 1 = Neutroamine
-| resource 1 amount = 2
-| bulk product amount = 4
-<!-- Technical -->
-| defName = Penoxycyline
-| drug category = medical
-| food preference = NeverForFood
-| preferability = NeverForNutrition
-| is pleasure drug = false
-<!-- Unused -->
 | always haulable = true
+| def name = Penoxycyline
+| description = A drug for blocking various infections. Blocks malaria, sleeping sickness, and plague. Take every five days.
+| deterioration rate base = 2.0
 | draw gui overlay = true
+| flammability base = 1.0
+| food preference = NeverForFood
 | graphic class = Graphic_StackCount
 | graphic path =  Things/Item/Drug/Penoxycyline
 | label = penoxycyline
+| beauty base = -6
+| market value base = 32
+| max hit points base = 50
+| mass base = 0
+| max num to ingest at once = 1
+| nutrition base = 0
 | parent name = MakeableDrugPillBase
+| path cost = 15
+| preferability =
 | resource readout priority = Last
+| rotatable = false
 | selectable = true
 | social properness matters = true
+| sound eat =
+| stack limit = 400
+| taste =
+| tech level = industrial
 | thing class = Drugs
+| ticker type =
 | use hit points = true
-<!--- Drug Parameters -->
+| work to make base = 9
+<!--
+- Drug Parameters -->
+| addictiveness = 0
+| blood filtration factor =
+| blood filtration offset =
+| blood pumping factor =
+| blood pumping offset =
+| breathing factor =
+| breathing offset =
+| consciousness factor =
+| consciousness offset =
+| drug category = medical
+| global work speed offset =
+| hearing factor =
+| hearing offset =
+| hunger factor =
+| hunger offset =
+| is pleasure drug = false
+| joy kind =
+| joy offset =
+| manipulation factor =
+| manipulation offset =
+| metabolism factor =
+| metabolism offset =
+| moving factor =
+| moving offset =
+| pain factor =
+| pain offset =
 | prevents infection = malaria, sleeping sickness, plague
-}}
+| rest fall factor =
-'''Penoxycyline''' is a [[drug]] that prevents users from catching a select following of [[disease]]s.
+| rest offset =
+| sight factor =
-== Acquisition ==
+| sight offset =
-Penoxycyline can be crafted at a [[{{P|Production Facility 1}}]] once the [[Research#{{P|Required Research}}|{{P|Required Research}}]] research project has been completed. Each dose require {{Required Resources}} and {{Ticks|{{P|Work To Make}}}} of work. Its [[Drug Synthesis Speed|synthesis speed]] is dependent on the [[Skills#Intellectual|Intellectual]] skill, and crafting experience is attributed to Intellectual. Note that [[Neutroamine]] can only be obtained from traders or found in cargo pods.
+| talking factor =
+| talking offset =
-It can also be [[Trade|bought]] from orbital, [[Outlander]], or [[Empire]] {{RoyaltyIcon}} traders, as well as Outlander and Empire [[faction base]]s.
-== Summary ==
-Penoxycyline completely prevents users from catching any of the following [[disease]]s while its "high" is active:
-* [[Malaria]]
-* [[Plague]]
-* [[Sleeping sickness]]
-Despite the wording of the description, it does nothing to prevent or treat [[infection]]s, or any other diseases or ailments besides the three above.
+}}</noinclude>
+<noinclude>
+{{Info|A drug for blocking various infections. Blocks malaria, sleeping sickness, and plague. Take every five days.
+}}</noinclude>
-When the [[Events#Disease (Type)|Disease event]] occurs, pawns that were protected from getting the disease by penoxycyline will be specifically noted as such. Penoxycyline does nothing to treat pre-existing diseases.
+<includeonly>
+{|class = "wikitable c03"
+|-
+!colspan="2" scope="col" style="text-align: left" | Drug info
+|-
+|Addictiveness ||  {{#show: Penoxycyline | ?addictiveness | link=none }}%
+|-
+|Market value || ${{#show: Penoxycyline | ?Market Value Base | link=none }}.00
+|-
+|Hit points || {{#show: Penoxycyline | ?Max Hit Points Base | link=none }}
+|-
+|Work to make || {{#show: Penoxycyline | ?Work To Make Base | link=none }}
+|}
+</includeonly>
-Penoxycyline is not addictive and has no direct side effects. Penoxycyline ''can'' contribute to [[overdose]]s, increasing severity by 0.08-0.14 per dose consumed. This severity is not enough to cause any health effect on its own. However, it can cause minor overdoses when taken along with [[hard drugs]].
+<noinclude>
+==Gameplay Overview==
+Penoxycyline is a medical drug in RimWorld which was introduced in Alpha 16, and succeeds Malari-Block. Unlike its predecessor, Penoxycyline blocks against 3 diseases: [[malaria]], [[sleeping Sickness|sleeping sickness]], and the dreaded [[plague]] - whereas Malari-block only blocked against malaria.
-== Analysis ==
+Like Malari-Block; Penoxycyline can either be purchased from traders, or crafted at a [[drug lab]] - but for a mere 3 [[neutroamine]] as opposed to the 5 which Malari-block took. However, in order to make Penoxycyline, you need to have [[research#PenoxycylineProduction|penoxycyline production]] researched, which in turn requires [[research#DrugProduction|drug production]], and Neutroamine has to either be purchased from traders, or found in cargo pods.
-Diseases usually aren't a fatal problem by the time you can get a good supply of [[neutroamine]] and have the [[Research#{{P|Required Research}}|{{P|Required Research}}]] research. For an otherwise healthy colonist: a decent doctor, in a clean hospital, using [[herbal medicine]] or [[medicine]] is usually enough to treat the disease (so long as the colonist rests for the duration). However, this drug can still be helpful.
-Penoxycyline can reduce the time spend resting in bed, especially in tropical biomes where disease is prevalent and sleeping sickness is possible. If you don't want to use penoxycyline on every colonist, you can reserve it for your doctors. This prevents your doctors from getting sick when a disease outbreak occurs. It can also be used on sickly pawns for obvious reasons. If you can afford the neutroamine cost (and won't be using it for [[medicine]], [[wake-up]], or [[go-juice]]), then this drug is a net positive.
+Penoxycyline can be administered if one has one of the diseases it protects against, and doing so will boost the immunity to 61% if it's lower than that.
-While the in-game description says to ''"Take every five days"'', the effect actually lasts just over than a half-day longer. This gives pawns some leeway, in case colonists don't consume the pills promptly. Set a [[drug policy]] to tell the pawns to take one every 5 days and keep one in the inventory to take as soon as possible, or be cheap, set it to "6 days" and live dangerously.
+Penoxycycline offers true immunity to plague & sleeping sickness for 12 hours, and malaria for 8 hours. After that period, it reduces the probably of that particular pawn getting sick (diseases cannot be acquired at 60%+ immunity, and Penoxy sets it to 61%, so there is a brief time before it decays below the threshold)
-== Gallery ==
+The weird part is that the game first picks how many pawns will get sick, regardless of immunity, and then next picks which pawns get sick, weighted by immunity. If only one of your pawns has taken penoxy, and took it 24 hours ago, that pawn is 1/50th as likely to get sick as the other pawns. But if all of your pawns have taken it 24 hours ago, they're all just as likely to get sick and the same number of pawns total will get sick. But they'll still be starting at 59% immunity, pretty much guaranteeing survival, and a very short period of actual sickness. (A young, healthy pawn will be at 90%+ immunity when the plague/sleeping sickness is revealed; malaria never revealed at all).
-<gallery>
-Penoxycyline a.png|One penoxycyline
-Penoxycyline b.png|Stack of penoxycyline
-</gallery>
-== Version history ==
+For plague & sleeping sickness, I would not recommend Penoxycycline prophylaxis for all healthy pawns; it can be taken reactively and still add 30%+ immunity, eliminating the need for bed rest or treatment to survive (and if treatment is provided it won't reach serious stages).
-* [[Version/0.15.1279|0.15.1279]] - Added as '''Malari-block''', and only prevents [[Malaria]]
-* [[Version/0.16.1393|0.16.1393]] - Reworked. Renamed from '''Malari-block''' to '''Penoxycyline ''' and now prevents a wide variety of infections. Cost decreased from 5 [[neutroamine]] to 3.
-* [[Alpha 17]] - Cost is further reduced from 3 to 2 neutroamine. It also received an overhaul, such that instead of instantly boosting disease immunity to 61%, it now provides true immunity and cannot reactively increase immunity against a disease that is already in progress.
-{{Nav/drugs}}
+Malaria does need proactive Penoxycycline. A healthy pawn will develop 55% immunity in the 4.6 days it takes to reveal itself, so reactive penoxy only adds 5%. Penoxy taken every 5 days will maintain a minimum of 46% immunity to malaria, so healthy pawns will never have a visible Malaria infection. But taken every 9 days, a healthy pawn will still develop immunity before malaria hits Major severity without any treatment or bed rest. A solo jungle explorer looking to conserve their supply might stretch it out to every 12 days (which will avoid extreme without any treatment or bed rest), or if they're particularly brave/desperate, every 15 days (but then there is a small risk that bed rest will be necessary). Taken every 20 days, Penoxy offers no guaranteed immunity, but on average will cut off 2.5 days before immunity is acquired.
+</noinclude>
-[[Category:Drug]] [[Category:Medical Drug]]
+<noinclude>
+{{nav/drugs}}
+</noinclude>