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Certain tolerances can directly cause chronic health problems. [[Smokeleaf]] tolerance above 36% can cause lung [[carcinoma]] and above 45% [[asthma]], [[beer]] above 45% can cause liver [[cirrhosis]] and [[carcinoma]], and [[psychite]] tolerance ([[Flake]]/[[Psychite tea]]/[[Yayo]]) above 45% can cause [[chemical damage]] to the [[kidney]]. Tolerance to [[ambrosia]] has no special ill effect, while the other drugs have no tolerances.
 
Certain tolerances can directly cause chronic health problems. [[Smokeleaf]] tolerance above 36% can cause lung [[carcinoma]] and above 45% [[asthma]], [[beer]] above 45% can cause liver [[cirrhosis]] and [[carcinoma]], and [[psychite]] tolerance ([[Flake]]/[[Psychite tea]]/[[Yayo]]) above 45% can cause [[chemical damage]] to the [[kidney]]. Tolerance to [[ambrosia]] has no special ill effect, while the other drugs have no tolerances.
  
Tolerance gain per dose scales inversely with [[body size]]. It can be calculated with the following formula:
+
Tolerance gain per dose scales inversely with [[body size]]. It can be calulated with the following formula:
  
<code>tolerance gain = tolerance per dose / body size</code>
+
<code>tolerance gain = tolerance per dose / body size^2</code>
  
 
[[Children]] {{BiotechIcon}} and small [[animal]]s can therefore get addicted much easier than an adult would.
 
[[Children]] {{BiotechIcon}} and small [[animal]]s can therefore get addicted much easier than an adult would.
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** [[Go-juice]] doesn't, despite costing yayo to create.
 
** [[Go-juice]] doesn't, despite costing yayo to create.
  
Current safe dose intervals (days) for humans based on age groups.  
+
Current safe dose intervals (days) for humans based on age groups. '''NOTE''': The in game "Safe Dose Intervals" for pawns 0 to 17 are not accurate. It is unclear whether the calculation or the display is bugged.
 
<div><li style="display: inline-table;">
 
<div><li style="display: inline-table;">
 
{| {{STDT| sortable c_25 text-center}} <!-- FORMULA: tolerance per dose / body size^2 / tolerance decreases rate OR SIMPLER: safe dose interval for adult human / body size^2 -->
 
{| {{STDT| sortable c_25 text-center}} <!-- FORMULA: tolerance per dose / body size^2 / tolerance decreases rate OR SIMPLER: safe dose interval for adult human / body size^2 -->
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|-
 
|-
 
! [[Ambrosia]]     
 
! [[Ambrosia]]     
| {{#expr: 1.6 / 0.2 round 2}} || {{#expr: 1.6 / 0.35 round 2}} || {{#expr: 1.6 / 0.58 round 2}} || {{#expr: 1.6 / 0.8 round 2}} || 1.6
+
| {{#expr: 1.6 / 0.2^2 round 2}} || {{#expr: 1.6 / 0.35^2 round 2}} || {{#expr: 1.6 / 0.58^2 round 2}} || {{#expr: 1.6 / 0.8^2 round 2}} || 1.6
 
|-
 
|-
 
! [[Beer]]        
 
! [[Beer]]        
| {{#expr: 1  / 0.2 round 2}} || {{#expr: 1  / 0.35 round 2}} || {{#expr: 1  / 0.58 round 2}} || {{#expr: 1  / 0.8 round 2}} || 1
+
| {{#expr: 1  / 0.2^2 round 2}} || {{#expr: 1  / 0.35^2 round 2}} || {{#expr: 1  / 0.58^2 round 2}} || {{#expr: 1  / 0.8^2 round 2}} || 1
 
|-
 
|-
 
! [[Psychite tea]]  
 
! [[Psychite tea]]  
| {{#expr: 2  / 0.2 round 2}} || {{#expr: 2  / 0.35 round 2}} || {{#expr: 2  / 0.58 round 2}} || {{#expr: 2  / 0.8 round 2}} || 2
+
| {{#expr: 2  / 0.2^2 round 2}} || {{#expr: 2  / 0.35^2 round 2}} || {{#expr: 2  / 0.58^2 round 2}} || {{#expr: 2  / 0.8^2 round 2}} || 2
 
|-
 
|-
 
! [[Smokeleaf joint]]     
 
! [[Smokeleaf joint]]     
| {{#expr: 2  / 0.2 round 2}} || {{#expr: 2  / 0.35 round 2}} || {{#expr: 2  / 0.58 round 2}} || {{#expr: 2  / 0.8 round 2}} || 2
+
| {{#expr: 2  / 0.2^2 round 2}} || {{#expr: 2  / 0.35^2 round 2}} || {{#expr: 2  / 0.58^2 round 2}} || {{#expr: 2  / 0.8^2 round 2}} || 2
 
|}
 
|}
 
</li></div>
 
</li></div>
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* Beer, smokeleaf, ambrosia, and psychite needs fall by 50% per day.
 
* Beer, smokeleaf, ambrosia, and psychite needs fall by 50% per day.
 
* Wake-up and go-juice needs fall by 33.3% per day.
 
* Wake-up and go-juice needs fall by 33.3% per day.
* Luciferium need falls by 15% per day, so that it must be taken every 6 days.
+
* Luciferium need falls by 15% per day, so that it must be taken every 6.667 days.
  
 
This is separate from the addiction (%) in the ''Health'' tab, which is the progress towards overcoming an addiction. See [[#Addiction progress|Addiction progress]] for that.
 
This is separate from the addiction (%) in the ''Health'' tab, which is the progress towards overcoming an addiction. See [[#Addiction progress|Addiction progress]] for that.
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* [[Version/1.2.2719|1.2.2719]] - Direct button to use drugs from inventory: This makes combat drugs more usable.
 
* [[Version/1.2.2719|1.2.2719]] - Direct button to use drugs from inventory: This makes combat drugs more usable.
 
* [[Version/1.4.3580|1.4.3580]] - Fix: Consume drug commands not appearing.
 
* [[Version/1.4.3580|1.4.3580]] - Fix: Consume drug commands not appearing.
* [[Version/1.5.4062|1.5.4062]] - Drug tolerance gain is now divided by body size and not body size squared - this also had the effect of making the suggested safe dose intervals for children correct.
 
  
 
{{Nav/drugs}}
 
{{Nav/drugs}}
 
[[Category:Items]]
 
[[Category:Items]]

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